Better integration of chemical pollution research will further our understanding of biodiversity loss | Nat Ecol Evol

antiSMASH 7.0: New and improved predictions for detection, regulation, chemical structures and visualisation | Nucleic Acids Res

MIBiG 3.0: A Community-driven Effort to Annotate Experimentally Validated Biosynthetic Gene Clusters | Nucleic Acids Res

A Microbiome-Dependent Gut–Brain Pathway Regulates Motivation for Exercise | Nature

Navigating and Expanding the Roadmap of Natural Product Genome Mining Tools | Beilstein J. Org. Chem.

Atropopeptides are a Novel Family of Ribosomally Synthesized and Posttranslationally Modified Peptides with a Complex Molecular Shape | Angew. Chem. Int. Ed.

Complex peptide natural products: Biosynthetic principles, challenges and opportunities for pathway engineering | Synth Syst Biotechnol

Bacillimidazoles A−F, Imidazolium-Containing Compounds Isolated from a Marine Bacillus | Mar. Drugs

Modular Halogenation, α-Hydroxylation, and Acylation by a Remarkably Versatile Polyketide Synthase | Angew. Chem. Int. Ed.

Hidden Treasures: Microbial Natural Product Biosynthesis off the Beaten Path | mSystems

Evolution of combinatorial diversity in trans-acyltransferase polyketide synthase assembly lines across bacteria | Nature Communications

A community resource for paired genomic and metabolomic data mining | Nature Chemical Biology

Specialized Metabolites Reveal Evolutionary History and Geographic Dispersion of a Multilateral Symbiosis | ACS Central Science

A multiproducer microbiome generates chemical diversity in the marine sponge Mycale hentscheli | Proceedings of the National Academy of Sciences

Research Tales from the Clardy Laboratory: Function-Driven Natural Product Discovery | Journal of Natural Products

Total synthesis reveals atypical atropisomerism in a small-molecule natural product, tryptorubin A | Science

Synergism of anisotropic and computational NMR methods reveals the likely configuration of phormidolide A | Chemical Communications

Bacterial terpene biosynthesis: challenges and opportunities for pathway engineering | Beilstein Journal of Organic Chemistry

Pyonitrins A–D: Chimeric Natural Products Produced by Pseudomonas protegens | Journal of the American Chemical Society

Automated structure prediction of trans-acyltransferase polyketide synthase products | Nature Chemical Biology

In plaque-mass spectrometry imaging of a bloom-forming alga during viral infection reveals a metabolic shift towards odd-chain fatty acid lipids | Nature Microbiology

A Polyketide Synthase Component for Oxygen Insertion into Polyketide Backbones | Angewandte Chemie

Bipartite interactions, antibiotic production and biosynthetic potential of the Arabidopsis leaf microbiome | Nature Microbiology

An Unusual Flavin-Dependent Halogenase from the Metagenome of the Marine Sponge Theonella swinhoei WA | ACS Chemical Biology

Insights into the lifestyle of uncultured bacterial natural product factories associated with marine sponges | Proceedings of the National Academy of Sciences

Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking | Nature Biotechnology

Metabolic footprint of epiphytic bacteria on Arabidopsis thaliana leaves | The ISME Journal

Biosynthesis of polyketides by trans-AT polyketide synthases | Natural Product Reports

Minimum Information about a Biosynthetic Gene cluster | Nature Chemical Biology

Metabolic and evolutionary origin of actin-binding polyketides from diverse organisms | Nature Chemical Biology

Nostopeptolide plays a governing role during cellular differentiation of the symbiotic cyanobacterium Nostoc punctiforme | Proceedings of the National Academy of Sciences

Recent advances in genome-based polyketide discovery | Current Opinion in Biotechnology

Matrix-free single-cell LDI-MS investigations of the diatoms Coscinodiscus granii and Thalassiosira pseudonana | Journal of Mass Spectrometry

An environmental bacterial taxon with a large and distinct metabolic repertoire | Nature

Genome Mining Reveals trans‐AT Polyketide Synthase Directed Antibiotic Biosynthesis in the Bacterial Phylum Bacteroidetes | ChemBioChem