Evolution of combinatorial diversity in trans-acyltransferase polyketide synthase assembly lines across bacteria | Nature Communications

A community resource for paired genomic and metabolomic data mining | Nature Chemical Biology

Specialized Metabolites Reveal Evolutionary History and Geographic Dispersion of a Multilateral Symbiosis | ACS Central Science

A multiproducer microbiome generates chemical diversity in the marine sponge Mycale hentscheli | Proceedings of the National Academy of Sciences

Research Tales from the Clardy Laboratory: Function-Driven Natural Product Discovery | Journal of Natural Products

Total synthesis reveals atypical atropisomerism in a small-molecule natural product, tryptorubin A | Science

Synergism of anisotropic and computational NMR methods reveals the likely configuration of phormidolide A | Chemical Communications

Bacterial terpene biosynthesis: challenges and opportunities for pathway engineering | Beilstein Journal of Organic Chemistry

Pyonitrins A–D: Chimeric Natural Products Produced by Pseudomonas protegens | Journal of the American Chemical Society

Automated structure prediction of trans-acyltransferase polyketide synthase products | Nature Chemical Biology

In plaque-mass spectrometry imaging of a bloom-forming alga during viral infection reveals a metabolic shift towards odd-chain fatty acid lipids | Nature Microbiology

A Polyketide Synthase Component for Oxygen Insertion into Polyketide Backbones | Angewandte Chemie

Bipartite interactions, antibiotic production and biosynthetic potential of the Arabidopsis leaf microbiome | Nature Microbiology

An Unusual Flavin-Dependent Halogenase from the Metagenome of the Marine Sponge Theonella swinhoei WA | ACS Chemical Biology

Insights into the lifestyle of uncultured bacterial natural product factories associated with marine sponges | Proceedings of the National Academy of Sciences

Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking | Nature Biotechnology

Metabolic footprint of epiphytic bacteria on Arabidopsis thaliana leaves | The ISME Journal

Biosynthesis of polyketides by trans-AT polyketide synthases | Natural Product Reports

Minimum Information about a Biosynthetic Gene cluster | Nature Chemical Biology

Metabolic and evolutionary origin of actin-binding polyketides from diverse organisms | Nature Chemical Biology

Nostopeptolide plays a governing role during cellular differentiation of the symbiotic cyanobacterium Nostoc punctiforme | Proceedings of the National Academy of Sciences

Recent advances in genome-based polyketide discovery | Current Opinion in Biotechnology

Matrix-free single-cell LDI-MS investigations of the diatoms Coscinodiscus granii and Thalassiosira pseudonana | Journal of Mass Spectrometry

An environmental bacterial taxon with a large and distinct metabolic repertoire | Nature

Genome Mining Reveals trans‐AT Polyketide Synthase Directed Antibiotic Biosynthesis in the Bacterial Phylum Bacteroidetes | ChemBioChem