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A multiproducer microbiome generates chemical diversity in the marine sponge Mycale hentscheli | Proceedings of the National Academy of Sciences
Total synthesis reveals atypical atropisomerism in a small-molecule natural product, tryptorubin A | Science

Genome Mining Reveals trans‐AT Polyketide Synthase Directed Antibiotic Biosynthesis in the Bacterial Phylum Bacteroidetes | ChemBioChem

2010

Evolution of combinatorial diversity in trans-acyltransferase polyketide synthase assembly lines across bacteria | Nature Communications

2021, Highlights

Better integration of chemical pollution research will further our understanding of biodiversity loss | Nat Ecol Evol

2023

Automated structure prediction of trans-acyltransferase polyketide synthase products | Nature Chemical Biology

2019, Highlights

Our latest news

We keep you up to date about our latest publications and developments on Twitter. Follow us @Helfrich_lab

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natprodreports Nat. Prod. Reports @natprodreports ·
8 Apr

🔓Don't miss this #OpenAccess article in our latest issue by Eric Helfrich et al. @goetheuni looking at the role and mechanisms of canonical and non-canonical tailoring enzymes in bacterial terpenoid biosynthesis

Check it out in full on our website👇

HelfrichLab

Explorative Natural Product Genomics.

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