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Modular Halogenation, α-Hydroxylation, and Acylation by a Remarkably Versatile Polyketide Synthase | Angew. Chem. Int. Ed.
Evolution of combinatorial diversity in trans-acyltransferase polyketide synthase assembly lines across bacteria | Nature Communications

Insights into the lifestyle of uncultured bacterial natural product factories associated with marine sponges | Proceedings of the National Academy of Sciences

2017

Automated structure prediction of trans-acyltransferase polyketide synthase products | Nature Chemical Biology

2019, Highlights

A Machine Learning-Based Genome Mining Approach Reveals Unprecedented Biarylitide Diversity | JACS Au

2026

MIBiG 3.0: A Community-driven Effort to Annotate Experimentally Validated Biosynthetic Gene Clusters | Nucleic Acids Res

2023

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natprodreports

Nat. Prod. Reports

@natprodreports ·
8 Apr 2025

🔓Don't miss this #OpenAccess article in our latest issue by Eric Helfrich et al. @goetheuni looking at the role and mechanisms of canonical and non-canonical tailoring enzymes in bacterial terpenoid biosynthesis

Check it out in full on our website👇
https://pubs.rsc.org/en/content/articlelanding/2025/np/d4np00048j

HelfrichLab

Explorative Natural Product Genomics.

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